It was expressed focally in the oral epithelium, dental lamina, outer enamel epithelium, stratum intermedium and stellate reticulum at cap and bell stages. 结果:COX-2在牙胚发育期间存在特异的时空分布模式,其阳性表达主要在牙胚发育帽状期、钟状期的口腔上皮、牙板上皮、外釉、中间层和星网状层。
Tooth is an organ of multi-germinal layer origin, which developed through the complicated reciprocal interaction between dental epithelium and mesenchyme precisely modulated by signal network constituted by a series of signal molecules. 牙齿是一种多胚层起源的器官,是胚胎期的牙源性上皮和间充质在一系列信号分子组成的信号网络的严密调控下,发生复杂的交互式作用而形成的。
Odontogenous mesenchymal tissue can differentiate into dentin and dental nucleus induced by odontogenous epithelium, and odontogenous epithelium can also develop into enamel organ induced by odontogenous mesenchymal tissue. 在牙源性上皮的诱导下,牙源性间充质进一步分化形成牙本质和牙髓,而牙源性上皮也在牙源性间充质的诱导下发育形成成釉器。
Objective: Tooth morphogenesis is a complex multifactorial process that involves sequential and reciprocal interactions between dental epithelium and the neural crest-derived mesenchyme. 目的:牙胚发育是一个复杂的、多因素参与的过程,它是上皮和间充质细胞之间相互作用的结果。
The tooth development is dependent on the mutual induction between dental epithelium and mesenchymal. 牙齿的发育是由牙上皮和牙间充质之间的相互诱导产生的。